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Dr. Meyya Meyyappan, Director at the Center for Nanotechnology at the NASA Ames Research Center, has highlighted the advantages of nanoscale vacuum devices which include resistance to hard radiation and significantly improved operating frequencies.
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While the cavity is not technically a vacuum it contains so few atoms of any other material, such as oxygen, it is functionally the same. This also gives the vacuum nanoscale device an advantage in space where hard radiation can disrupt an electron's travel through silicon leading to errors or sometimes permanent failure.
Dr Meyyappan estimates that vacuum nanoscale components will run ten times faster than the best conventional silicon chips and who knows what advances the future will hold. Faster chips will aid in signal processing and more capable software defined radios.
Do you want to monitor every CW & PSK31 transmission on the 40M band at once? With a vacuum "tube" rig you may be able to!